Questions, answered.

Three steps. First, you pick your treatment from our catalog and check out through Shopify's secure checkout. Second, you complete a HIPAA-compliant medical intake form linked from your order confirmation — this takes 5–10 minutes and gives your clinician the clinical info they need to prescribe safely. Third, a licensed clinician licensed in your state reviews your intake before fulfillment, approves your protocol, and your medication moves to fulfillment after approval.

If a clinician can't safely approve your treatment, your purchase is refunded in full within 48 hours — no action needed on your end.

No. You pick the treatment directly from our catalog. The clinical intake happens after checkout — that's where a clinician actually needs your health history, current medications, allergies, and contraindications to write a safe prescription. If we determined upfront that treatment isn't right for you, we refund your purchase in full.

Approved treatment moves through pharmacy fulfillment after clinical review. Here's the typical timeline: checkout (T+0), medical intake (+5 min), clinician review (before fulfillment), pharmacy compounding (+24–48 hours), shipping (the available shipping lane after approval).

GLP-1 medications ship overnight in temperature-controlled packaging. Oral medications typically ship 2-day.

Our clinicians support patients in all 50 states. If a treatment has a state-specific prescribing or shipping restriction, we flag it during checkout or medical review and tell you exactly what happens next.

No — we're unisex. Our catalog includes protocols for weight loss, sexual wellness, hormone therapy (including both male and female HRT), skin, hair, sleep, recovery, and cognitive. Amie was originally founded with a women's health focus and that remains a specialty, but we serve all adult patients who are clinically appropriate candidates.

You must be 18 or older to order. Some specific protocols have higher minimum ages (GLP-1 weight loss medications, for example, require patients to be 18+). Clinicians reserve the right to decline treatment based on clinical judgment regardless of age.

No. Each patient must create their own account, complete their own medical intake, and be personally reviewed by a clinician. This is required both for regulatory compliance and patient safety — a clinician can't safely prescribe for someone they haven't personally evaluated.

Compounded medications are custom-prepared by licensed pharmacists using clinician-reviewed active ingredients, tailored to each patient's dose. This lets us offer doses and formulations (like combined semaglutide + B12, or custom-strength topical estrogen) that aren't commercially manufactured.

If prescribed, treatment is fulfilled through licensed pharmacy partners after clinical review. We avoid pharmacy-accreditation claims unless a specific partner credential is verified for the exact route.

The active ingredients we use are FDA-approved. The specific compounded formulations aren't individually FDA-approved because they're prepared per-patient, not mass-manufactured. Compounding is regulated under federal and state pharmacy rules, and fulfillment only begins after licensed clinician approval.

Pharmacy partners follow applicable quality and dispensing requirements for the medication prescribed.

The active ingredient is the same: semaglutide. The difference is the formulation. Our compounded semaglutide often includes additional ingredients like B12 or methylcobalamin to support energy and reduce side effects. It's also available in a wider range of doses than the commercial branded versions, letting clinicians titrate more precisely.

Compounded semaglutide is a legal alternative when the branded versions are in FDA-declared shortage, which Ozempic and Wegovy currently are.

Depends on the protocol. General guidelines:

• GLP-1 weight loss (semaglutide, tirzepatide) — appetite suppression in week 1; measurable weight loss in 4–8 weeks.
• Hormone replacement (estrogen, progesterone, testosterone) — 2–4 weeks for initial symptom relief; full benefit in 2–3 months.
• Spark / PT-141 (libido) — effect within 30–60 minutes of dosing; doesn't build up over time.
• Topical skin treatments (tretinoin, estriol face cream) — 6–12 weeks for visible change.
• Hair regrowth (finasteride + minoxidil) — 3–6 months for early regrowth; 12 months for full effect.

Yes. Your prescribing clinician can adjust your dose, change your protocol, or recommend a different medication at any time. Most dose changes happen at the 1-month and 3-month checkpoints based on your response and any side effects. Message your clinician directly from your dashboard — they'll respond within the business day.

Message your clinician directly from your dashboard. They'll evaluate whether the side effects are expected (many resolve on their own after the first 2–4 weeks), whether to adjust your dose, or whether to switch protocols. If side effects are severe or urgent, contact emergency services or go to the nearest ER — don't wait.

All prescriptions include a detailed list of common, less-common, and rare side effects to watch for.

We define "not working" at the 8–12 week mark, depending on the protocol. If you haven't seen the expected results in that timeframe, your clinician will reassess — usually adjusting dose, changing formulation, or recommending a complementary protocol. We're committed to finding what actually works for you, not just refilling the original prescription on autopilot.

Usually yes, but the intake form asks for all current medications specifically so your clinician can check for interactions. Some combinations are fine, some require dose adjustments, and a few are contraindicated. Always update your medication list in your dashboard when anything changes — your clinician will be notified.

Yes. Our supplement line is formulated by our medical team — specific ingredients and doses chosen based on clinical literature, not trend-following. All supplements are produced in GMP-certified U.S. facilities and third-party tested for purity and potency. Supplements don't require a prescription or medical intake — you can order them directly.

At checkout. Your card is charged through Shopify's secure payment when you complete your order, just like any other e-commerce purchase.

If a clinician subsequently can't approve your treatment after reviewing your medical intake, your purchase is refunded in full within 48 hours. You don't pay for a prescription you never receive.

If after reviewing your medical intake a clinician determines treatment isn't safe or appropriate for you, we refund your purchase in full within 48 hours. No support ticket, no refund form, no restocking fee.

You'll get a clear explanation of why treatment was declined, and often a referral to what might be a safer alternative.

We don't bill insurance directly — this lets us keep prices consistent and predictable. Many patients use HSA/FSA cards (which are accepted), and we can provide itemized receipts for out-of-network reimbursement submissions. Check with your insurance provider about what's reimbursable.

No. The price you see on each product page is the monthly price you pay — including the clinician visit, prescribing, ongoing follow-up messaging, and shipping (free over $100). No consult fees, no platform fees, no renewal fees.

Yes for select protocols. Where available, the quarterly (3-month) and annual (12-month) plans show as options on the product page. Quarterly saves ~10% per month vs. monthly; annual saves ~20%. Both plans auto-renew but you can pause, skip, or cancel from your dashboard.

From your dashboard → Billing → Payment method. Add a new card, remove an old one, or set a default. Any changes take effect on your next scheduled refill. We use Shopify's native subscription billing which means your payment info is stored with Shopify, not us directly.

After a licensed clinician approves treatment, fulfillment moves through the pharmacy process. Timing varies by treatment, pharmacy workflow, and shipping carrier. You'll get tracking when your package leaves the pharmacy.

Free shipping on orders over $100. Orders under $100 ship for a flat $6.95. Prescription orders are eligible for free shipping regardless of amount.

GLP-1 medications (semaglutide, tirzepatide) and other temperature-sensitive prescriptions ship overnight in insulated packaging with ice packs or gel packs, depending on season. The packaging is validated to maintain temperature for 48+ hours — plenty of buffer for overnight delivery.

If your fulfillment is delayed or the ice packs are fully melted on arrival, message us immediately and we'll replace it at no cost.

Message us from your dashboard with photos (if damaged) or your tracking number (if lost). For most incidents we'll ship a replacement same-day or next-business-day at no cost. For significant delays outside our control (weather, carrier issues), we'll work with you on timing.

Yes. All fulfillments arrive in plain outer packaging with no Amie branding, no medication names, no health-related identifiers on the outside. The return address is our fulfillment partner, not a medical facility. Inside the package, everything is clearly labeled for your records.

Yes. Your medical intake, prescription history, clinician messages, and all health data are stored and transmitted in compliance with HIPAA. We use encrypted databases, encrypted transmission, and strict access controls. Only the clinicians reviewing your case and our care team can access your PHI, and every access is logged.

Not unless you tell them. We don't share your health information with external parties, including your primary care provider or insurance company. That said, we strongly encourage you to inform your other healthcare providers about any medications you're taking — including Amie prescriptions — so they can provide coordinated care.

Every Amie clinician is licensed, holds an active medical license in each state they practice in, has a clean DEA record, and carries malpractice insurance. We verify licenses every 90 days and require all clinicians to complete ongoing telemedicine and protocol-specific training.

Three groups: (1) the clinicians reviewing and managing your case, (2) our internal care team for support purposes, and (3) our pharmacy partners for the specific prescriptions they fulfill. We don't sell health data, don't share it with advertisers, and don't use it for marketing purposes.

Call 911 or go to the nearest emergency room immediately. Amie is not an emergency service. Our clinicians review cases asynchronously and cannot provide urgent care. If you're experiencing chest pain, severe allergic reaction, suicidal thoughts, or any other life-threatening symptoms, get in-person emergency care right away.

Yes. From your dashboard → Settings → Medical records. You can download your complete intake history, prescription history, clinician messages, and lab results (if any) as a PDF. We recommend keeping a copy for your other healthcare providers.

From your dashboard → Subscriptions → Manage. One click. Pause for a month, skip a fulfillment, or cancel entirely. No phone calls, no retention specialists, no six-question exit forms. Changes take effect immediately and you'll see them reflected in your next scheduled fulfillment.

From your dashboard → Messages → New message to clinician. Your prescribing clinician will respond directly — typically within the business day, faster for urgent messages. Messages are encrypted and stored as part of your medical record.

From your dashboard → Settings → Shipping & billing. Update your address, name, phone, and email. Changes apply to your next order. If you've already placed an order but it hasn't shipped yet, message support and we'll update it directly.

We respond within the business day for most inquiries. Medical questions route to your clinician directly. Billing, shipping, and account questions route to our care team. Messages sent outside business hours are answered first thing the next morning.

Yes. Every message you send gets read and replied to by a real person — our care team for support questions, your clinician for clinical questions. We don't route through triage bots or outsourced support. If you prefer phone, we offer scheduled callbacks for clinical questions; request one from your dashboard.

You're matched with a licensed clinician licensed in your state. Once matched, the same clinician manages your case ongoing — no bouncing between doctors each visit. You can see your clinician's credentials, specialty, and bio from your dashboard. Meet our providers on our reviews & providers page.

Depends on the medication. If prescribed, treatment is fulfilled through licensed pharmacy partners selected for the relevant category and route.

Your order confirmation includes the dispensing pharmacy's name and license information.

Prescription medication quality controls depend on the medication and pharmacy partner. When treatment is prescribed, fulfillment is routed through licensed pharmacy partners. Our supplement line is additionally third-party tested by independent labs, with test results published on each product page.

Clinician requests: yes, if they're available in your state. Include the request in your intake form comments, or message support after checkout. Pharmacy requests: no, we route based on specialty and capacity rather than patient preference, but you can see which pharmacy dispensed each fulfillment on your order history.